| 1965 | July 5, the University of Pisa founds the CNUCE (Centro Nazionale Universitario di Calcolo Elettronico) as a University computer center, and establishes a partnership with the IBM Scientific Center in Pisa (IBM 7090, 2 IBM 1401) |
| 1967 | DCMP (Digital Computer Music Program) |
| 1969 | IBM 1800 and IBM 360/30 |
| 1971 | IBM 360/67 with CP/CMS and OS/MVT-HASP |
| 1972 | Start of remote connections (dial-up, leased lines), interactive terminals, and remote printers/card readers |
| 1973 | IBM 370-155 OS/MVS-HASP |
| 1974 | RPCNET (Reel Project Computer NETwork) kick off |
| 1974 | IBM 370/168 with VM/CMS |
| 1974 | IBM 370/158 with OS/VS2-HASP |
| 1974 | CNUCE becomes an Institute of the CNR (National Research Council of Italy) |
| 1975 | Start of RSCS service |
| 1975 | CNUCE responsible for flight dynamics in the SIRIO project |
| 1976 | RPCNET prototype presentation |
| 1978 | Start of RPCNET service among CNR computer centers |
| 1978 | Flight manager in the launch of the first Italian satellite SIRIO |
| 1979 | Linguistics section becomes Institute of Computational Linguistics of CNR in Pisa |
| 1982 | OSIRIDE (Open Systems Interconnection Su Rete Italiana Dati Eterogenea) Open Systems Interconnection over Heterogeneous Italian Data Network project kick off |
| 1984 | CNUCE becomes a node of EARN (European Academic Research Network) |
| 1985-1987 | Flight dynamics system and data transmission system of the SIRIO2 satellite |
| 1985 | IBM SNA replaces RPCNET |
| 1986 | CNUCE goes on INTERNET |
| 1988-1994 | Mission operation team in SRL-1 SRL-2 flights |
| 1989-1990 | COLUMBUS navigation, rendezvous, and proximity operations |
| 1989-1990 | IRIS/LAGEOS-2 mission analysis and operations |
| 1990 | Responsible for reentry predictions for uncontrolled spatial objects |
| 1996 | Project representative in LEOP operations for ITALSAT F2 |