ITA-NTN is a structural project of SPOKE 2 - INTEGRATION OF NETWORKS AND SERVICES of the "RESearch and innovation on future Telecommunications systems and networks, to make Italy more smart” (RESTART) project, funded by the European Union – NextGenerationEU as part of the NRRP – M4C2, Investment 1.3, Call n. 341 of 15.03.2022 of the Ministry of University and Research (MUR) with 116 million euros, making RESTART the most important public R&D program ever implemented in the Telecommunications sector in Italy. The program has a duration of 3 years, starting from January 2023. ITA-NTN will define future integrated Terrestrial/Non-Terrestrial (T/NT) networks, where space network entities (unmanned aerial vehicles, aircraft, high-altitude platforms, and Geostationary and non-Geostationary satellites) cooperate with conventional and emerging terrestrial communication architectures to provide ubiquitous, resilient, and three-dimensional wireless connectivity around the world, supporting Mobile Broadband Reliable Low Latency Communications, massive Ultra Low Latency Communications, and Human-Centric Services. The resulting network will improve coverage, user experience, system capacity, service reliability and availability, and environmental sustainability of next generation communication infrastructure for the following verticals: transport, security, public safety, media, entertainment, eHealth, energy, agriculture, finance, automotive. It can provide high-speed connectivity in remote sites or in disaster-affected areas. From the technical perspective, the project will investigate free-space, optical, and radiofrequency communication links, conceive new physical transmission and channel access techniques, and design novel protocols and management facilities based on artificial intelligence and network softwarization. The project will contribute to the definition of the 6G currently ongoing at European and Worldwide level, while strongly reinforcing the Italian University and Industrial Research & Development position in this context.